NOTE: A faculty listing organized by research area is available here.

 

Catalina Achim

Catalina Achim

Biology-inspired chemistry   Research in my group is directed towards the synthesis and characterization of novel supramolecular structures containing transition metal ions, which offer the opportunity to employ the rich aspects of...

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Jinwoo Ahn

Jinwoo Ahn

  Our current research focuses on investigating the molecular and structural basis of HIV/host protein-protein interactions during early states of HIV cellular infection. Specifically We are focused on understanding mechanisms of...

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Sanford Asher

Sanford Asher

Protein folding, structure & dynamics by Raman spectroscopy Professor Asher's research program is interdisciplinary and brings together scientists in analytical chemistry, biophysical chemistry, materials science and physical chemistry to solve important scientific...

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Ivet Bahar

Ivet Bahar

Modeling & simulations of biomolecular dynamics Modeling and simulations of biomolecular structure & dynamics; statistical mechanics of polymers; conformational dynamics of proteins; coarse-grained simulations.             Education PhD 1986, Istanbul Technical University, TurkeyPostdoctoral Training 1987, University of...

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Panayiotis Benos

Panayiotis Benos

  The primary focus of my research is in the area of gene regulation and special emphasis is given to the understanding of the mechanisms that govern the specific DNA binding...

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Jeffrey Brodsky

Jeffrey Brodsky

Molecular Chaperones/Protein Quality Control All secreted proteins, and most that ultimately reside within the cell, must traverse the secretory pathway, a network of intracellular organelles housing the machines that help secreted...

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Guillermo Calero

Guillermo Calero

X-ray crystallography, Transcription, DNA repair, membrane  Structural studies of macromolecular complexes using X-ray crystallography; especially, macromolecular complexes involved in key cellular functions such as transcription, DNA-repair and GPCR signaling                 EducationPhD 1998-2003, Cornell...

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Lillian Chong

Lillian Chong

Natively unfolded proteins   We use molecular simulation methods to examine a variety of biological phenomena while pursuing questions that cannot be addressed by laboratory experiments.  Our research falls into three main areas: 1) Development...

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Rob Coalson

Rob Coalson

Theory of chemical dynamics Exact and approximate wavepacket dynamics techniques, developed in our group and elsewhere, have been utilized to investigate experimentally observable signatures of condensed ph ase quantum dynamics. Specific...

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James Conway

James Conway

Virus structure with cryo-EM       I study the structure and function of macromolecular complexes, such as virus capsids, using cryo-electron microscopy and combine this with subunit atomic models to extend interpretation into details of...

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Kris Dahl

Kris Dahl

Cell nucleus, lamins, nuclear lamina   We study mechanical and rheological properties of the nucleus. In deciphering the structural and mechanical elements of the cell's nucleus we hope to determine roles of...

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Alex Deiters

Alex Deiters

Optical Control of Cellular Processes Nature controls biological processes with exquisite spatial and temporal precision. In order to study and understand these processes, an equally precise external control element is required....

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Markus Deserno

Markus Deserno

Theoretical and computational biological physics I use both theoretical and computational techniques to study a varietyof fundamental biophysical questions that emerge on the (meso-)scaleof tens to hundreds of nanometers. For instance,...

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William Furey

William Furey

Enzyme crystallography   Determination and analysis of structure-function relationships in macromolecules of biological interest, including thiamin diphosphate dependent enzymes, immunoglobulins, bacterial toxins, digestive enzymes and other proteins. X-Ray Crystallography is the primary...

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Angela Gronenborn

Angela Gronenborn

Structural basis of signaling & gene regulation   Our research combines nuclear magnetic resonance (NMR) spectroscopy with Biophysics, Biochemistry, and Chemistry to investigate cellular processes at the molecular and atomic levels in...

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David Hackney

David Hackney

Molecular motors and ATP energy coupling The Hackney lab studies the mechanisms, regulation and structure of enzymes, with emphasis on the ways in which structure and mechanism are interrelated. Current research...

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Roger Hendrix

Roger Hendrix

Virus assembly, structure & evolution   The Hendrix lab studies virus assembly as a means to understand more general questions about protein structure, protein-protein and protein-DNA interactions, mechanisms and regulation of biological...

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Michael Hendrich

Michael Hendrich

Spectroscopy & characterization of Metalloenzymes & Biomimetic complexes     Metalloproteins are essential for the basic processes of life, including DNA synthesis, metabolism, photosynthesis, detoxification, and the chemical transformations of nitrogen, oxygen, and...

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Andrew Hinck

Andrew Hinck

NMR studies of TGF-beta family signaling proteins Research information In the Hinck laboratory, we are interested in utilizing the tools of structural biology to understand how the structure and dynamics of biological...

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Chien Ho

Chien Ho

NMR studies of allosteric proteins   The research goal in this laboratory is to understand the relationships between structure and function in biological systems by correlating information obtained from biochemical, biophysical, and...

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Seth Horne

Seth Horne

Study of synthetic protein analogues     Research in the Horne lab is focused on the design, synthesis and study of synthetic analogues of polypeptides and proteins. The cellular machinery underlying life is...

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Rieko Ishima

Rieko Ishima

NMR spectroscopy   The major objective of our research has been to determine protein structure and dynamics using nuclear magnetic resonance (NMR); spectroscopy, in order to elucidate protein function particularly relating to...

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Kabirul Islam

Kabirul Islam

CHEMICAL APPROACHES TO EPIGENETICS    Research information Research in the Islam lab seeks to understand the role of epigenetic mechanisms particularly chemical modifications on DNA and histones in eukaryotic gene regulation. We take...

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Saleem Khan

Saleem Khan

Replication initiator proteins, DNA helicases, & micro RNAs   Areas of research: Gene regulation by microRNAs; PcrA helicase-DNA interactions. Our laboratory is studying the mechanism by which the human papillomavirus (HPV) oncogenes alter...

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Kazunori Koide

Kazunori Koide

Organic synthesis & fluorescent sensors   Research in the Koide group is comprised of several interdisciplinary projects. Each project utilizes a combination of chemical and biological solutions to solve a complex problem....

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Maria Kurnikova

Maria Kurnikova

Molecular dynamics & function of channels   Currently research in my group focuses on theoretical/computational modeling of structure/function relationships and mechanisms of functioning of ion channel and receptor proteins. These proteins are...

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Frederick Lanni

Frederick Lanni

Mechanics of cells   The mechanical activities of non-muscle cells drive many processes in embryonic development, tissue maintenance and healing, immune cell migration and function, neuronal circuit formation, and progression of certain...

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Sanford Leuba

Sanford Leuba

Single-molecule spectroscopy of chromatin & molecular motors   Since the discovery of the nucleosome in the early 1970's, scientists have sought to correlate chromatin structure and dynamics with biological function. More recently, we...

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Mathias Lösche

Mathias Lösche

Peptide interactions with membranes; membrane-peripheral proteins; X-ray/neutron scattering   Our work focuses on the structural and dynamic characterization of biomimetic membranes (that is, simpler artificial mono- and bilayer systems that capture the fundamental...

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Danith Ly

Danith Ly

Genomics & proteomics   Our research lies at the interface of chemistry and biology, with emphasis on the development of chemical tools and application of genomics and proteomics technologies to solving problems...

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Patrick Moore

Patrick Moore

Mechanisms for human virus-induced carcinogenesis Our lab is jointly managed by Patrick Moore and Yuan Chang.  We work mainly on two viruses that we discovered, a herpesvirus (KSHV, 1994) and a...

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Eckard Münck

Eckard Münck

Mössbauer & EPR spectroscopy, DFT calculations Our group uses Mössbauer spectroscopy, Electron Paramagnetic Resonance and Density Functional Theory (and other methods when appropriate); to understand key states of iron-containing metalloproteins and...

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Patricia Opresko

Patricia Opresko

Mechanisms of DNA helicase action on telomeric substrates Maintenance of the genome is critical for the survival and health of an organism. Genomic mutations and alterations promote cancer, and the incidence...

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Guillermo Romero

Guillermo Romero

Protein regulation by lipids G-protein coupled receptors (GPCR) are the largest family of cell surface receptors found in mammalian organisms.  These receptors are a major target for drug development.  Dr. Romero...

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John Rosenberg

John Rosenberg

DNA Recognition by X-ray & statistical mechanics   My research philosophy is to bring a physical, problem-ori­ented ap­proach to the acquisition and interpretation of structural biomolecular information. I view biological molecules as...

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Gordon Rule

Gordon Rule

Protein ligand interactions by NMR   My research is directed at understanding inter-molecular interactions in biological systems. An understanding of these interactions is required if biological systems are to be comprehended at...

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Sunil Saxena

Sunil Saxena

  EPR spectroscopy The intellectual thrust of the Saxena Group is focused on developing Fourier Transform electron spin resonance and its application to otherwise inaccessible problems in biophysics. The coupling of electron...

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Thomas Smithgall

Thomas Smithgall

Cytoplasmic Tyrosine Kinase Structure, Function, and Chemical Biology My research program applies an interdisciplinary approach to a broad range of questions surrounding the roles of cytoplasmic protein-tyrosine kinase signaling pathways in...

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Robert Swendsen

Robert Swendsen

Computer simulations of biological molecules   My main area of research is solid state physics and statistical mechanics, with an emphasis on computer simulations. I have worked especially on thermodynamic phase transitions combining...

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Pei Tang

Pei Tang

NMR & computations of protein structures, dynamics, & drug effects   Research in the Tang Group focuses on the structures and dynamics of membrane proteins, which are the primary targets for many classes...

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Andrew VanDemark

Andrew VanDemark

Molecular mechanisms underlying transcription and cellular morphology My lab uses a variety of biophysical and biochemical techniques to identify and describe the molecular mechanisms that underlie a variety of important biological...

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Patrick van der Wel

Patrick van der Wel

Solid state NMR of membrane proteins & amyloid fibrils     The Van der Wel group uses solid state NMR spectroscopy and complementary structural and biophysical techniques to study the protein (mis)folding, protein aggregation,...

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Ben Van Houten

Ben Van Houten

Structure-function studies of nucleotide excision repair proteins  Structure-function Studies of Nucleotide Excision Repair Proteins. Faulty DNA repair can promote mutations, aging, cancer and cell death. The process by which protein components of repair...

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Alan Waggoner

Alan Waggoner

Fluorescence spectroscopy   Dr. Waggoner’s research has focused on development of fluorescence-based detection systems for biology and biotechnology. He spent 20 years at Amherst College then Carnegie Mellon University before establishing a...

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Ronald Wetzel

Ronald Wetzel

Amyloid structure & assembly   Aggregate structure. The protein aggregates associated with Alzheimer's Disease, Huntington's Disease, and other diseases tend to be highly ordered structures possessing, so far as we can establish, the...

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Peter Wipf

Peter Wipf

Bioorganic chemistry    Research in the Wipf Group focuses on the total synthesis of natural products, organometallic and heterocyclic chemistry, combinatorial, medicinal and computational chemistry. At the center of this research program...

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Yan Xu

Yan Xu

NMR of ion channels & low-affinity drug action   Research efforts in Dr. Xu's group are directed to three projects: (1); membrane protein structures and dynamics by NMR; (2); low-affinity drug interaction...

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Peijun Zhang

Peijun Zhang

High-resolution cryo-EM of macromolecular assemblies Our research is focused on structure and function of macromolecular assemblies using three-dimensional cryo-electron microscopy (cryoEM), combined with biochemical, biophysical and molecular biology methods. CryoEM is...

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