Our lab studies the HIV-1 protein Nef, and its host cell interaction partners. My project is focused on the interaction between Nef and Tec family kinases. I use X-ray crystallography and Surface Plasmon Resonance (SPR), among other biophysical techniques, to study this interesting structural interface. By studying the interaction it may be possible to design small molecules to disrupt Nef :Tec binding, thus helping to treat HIV infection.
Chemistry BS, West Virginia Wesleyan College, 2013
PhD Advisor: Dr. Thomas Smithgall
533 Bridgeside Point II
450 Technology Drive
Pittsburgh, PA 15219