Thesis title: Biophysical Investigations of Aβ Aggregation Process

Graduation date: Dec 2014

PhD Advisor: Dr. Ronald Wetzel (Dept. Structural Biology, University of Pittsburgh School of Medicine)


Research interests:

Saketh's work in Dr. Wetzel’s lab involved studying structural biology of protein aggregation diseases and the mechanism of fibril formation. His work mainly focused on Amyloid-beta peptide molecules which are implicated in Alzheimer’s disease upon aggregation. His research included elucidation of the secondary structural elements of these aggregates using standard techniques like hydrogen-deuterium exchange along with mass spectrometry, FTIR and Transmission Electron Microscopy.

Current location: post-doctoral researcher at Case Western, in the Surewicz lab



B.Tech. Industrial Biotechnology, Anna University, India. 2006

Ph.D., Molecular Biophysics & Structural Biology, University of Pittsburgh, 2014