Dr. Wesley Brown in the MD/PhD program at the University of Pittsburgh School of Medicine successfully passed his oral defense on July 20th and completed his Ph.D. degree. The title of his dissertation project is, “Conditional Control of Protein Function in Aquatic Embryos” under the supervision of Prof. Alexander Deiters. His work details the generation of conditional control over the activity of proteins and microRNA knockdown in zebrafish and Xenopus embryos. His talk focused on the development of optical control of a RASopathy disease-associated mutant of NRAS and optical control of microRNA-430 knockdown, both used to study their respective roles in zebrafish heart development. Wes will finish up his medical training over the next two years before applying for residency programs in internal medicine.