Currently, I work in Professor Hinck's Lab. He uses methods in structural biology and biophysics to investigate the TGF-β superfamily and their receptors. Since my long-term interests pertain to delivery systems, I'm interested in how the pro-domains of various TGF-β superfamily members (Pro-BMP-9 and -10, as well as Pro-TGF-β1,-β2, and -β3) create context specific release. To investigate these proteins and their interactions I am learning protein purification, protein crystallography, and protein-protein SPR. In terms of practical relevance, many of the proteins I work on are relevant to cardiovascular development and disease.
Education: B.S. SUNY Institute of Technology at Utica-Rome (Utica, NY) 2017
PhD Advisor: Dr. Andrew P. Hinck
BST3 Lab 2024
3501 Fifth Ave
Pittsburgh, PA 15260
email: TAS224 [at] pitt.edu
Capasso TL, Trucco SM, Hindes M, Schwartze T, Bloch JL, Kreutzer J, Cook SC, Hinck CS, Treggiari D, Feingold B, Hinck AP, Roman BL. (2020) In Search of "hepatic factor:" Lack of Evidence for ALK1 Ligands BMP9 and BMP10. Am J Respir Crit Care Med, in press doi: 10.1164/rccm.202005-1937LE.