Research Interests:
Currently, I work in Professor Hinck's Lab. He uses methods in structural biology and biophysics to investigate the TGF-β superfamily and their receptors. Since my long-term interests pertain to delivery systems, I'm interested in how the pro-domains of various TGF-β superfamily members (Pro-BMP-9 and -10, as well as Pro-TGF-β1,-β2, and -β3) create context specific release. To investigate these proteins and their interactions I am learning protein purification, protein crystallography, and protein-protein SPR. In terms of practical relevance, many of the proteins I work on are relevant to cardiovascular development and disease.
Education: B.S. SUNY Institute of Technology at Utica-Rome (Utica, NY) 2017
PhD Advisor: Dr. Andrew P. Hinck
Lab Address:
BST3 Lab 2024
3501 Fifth Ave
Pittsburgh, PA 15260
email: TAS224 [at] pitt.edu
Publications:
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Capasso TL, Trucco SM, Hindes M, Schwartze T, Bloch JL, Kreutzer J, Cook SC, Hinck CS, Treggiari D, Feingold B, Hinck AP, Roman BL. (2020) In Search of "hepatic factor:" Lack of Evidence for ALK1 Ligands BMP9 and BMP10. Am J Respir Crit Care Med, in press doi: 10.1164/rccm.202005-1937LE.